References

Abdulmalek OAAY, Husain KH, AlKhalifa HKAA, Alturani MMAB, Butler AE, Moin ASM Therapeutic applications of stem cell-derived exosomes. International Journal of Molecular Sciences. 2024; 25:(6) https://doi.org/10.3390/ijms25063562

Alqam M, Wamsley CE, Hitchcock T, Jones BC, Akgul Y, Kenkel JM Efficacy and tolerability of a microneedling device for treating wrinkles on the neck. Aesthet Surg J. 2022; 42:(10)1154-1160 https://doi.org/10.1093/asj/sjac085

Chawla S Split face comparative study of microneedling with PRP versus microneedling with vitamin C in treating atrophic post acne scars. Journal of Cutaneous and Aesthetic Surgery. 2014; 7:(4)209-212 https://doi.org/10.4103/0974-2077.150742

Dhurat R, Sukesh M, Avhad G, Dandale A, Pal A, Pund P A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichology. 2013; 5:(1)6-11 https://doi.org/10.4103/0974-7753.114700

Farshi S, Mansouri P Study of efficacy of microneedling and mesoneedling in the treatment of epidermal melasma: a pilot trial. J Cosmet Dermatol. 2020; 19:(5)1093-1098 https://doi.org/10.1111/jocd.13369

Glancey L Methods of hair restoration for men and women. J Aesthetic Nurs. 2023; 12:(1)19-23 https://doi.org/10.12968/joan.2023.12.1.19

Hong C, Zhang G, Zhang W Hair grows hair: dual-effective hair regrowth through a hair enhanced dissolvable microneedle patch cooperated with the pure yellow light irradiation. Applied Materials Today. 2021; 25 https://doi.org/10.1016/j.apmt.2021.101188

Tan J, Beissert S, Cook-Bolden F Evaluation of psychological well-being and social impact of atrophic acne scarring: a multinational, mixed-methods study. JAAD Int. 2021; 6:43-50 https://doi.org/10.1016/j.jdin.2021.11.006

Yang G, Chen Q, Wen D A therapeutic microneedle patch made from hair-derived keratin for promoting hair regrowth. ACS Nano. 2019; 13:(4)4354-4360 https://doi.org/10.1021/acsnano.8b09573

Yang K, Tang Y, Ma Y Hair growth promoting effects of 650 nm red light stimulation on human hair follicles and study of its mechanisms via RNA sequencing transcriptome analysis. Ann Dermatol. 2021; 33:(6)553-561 https://doi.org/10.5021/ad.2021.33.6.553

Zahra FT, Adil M, Amin SS, Mohtashim M, Bansal R, Khan HQ Efficacy of topical 5% 5-fluorouracil with needling versus 5% 5-fluorouracil alone in stable vitiligo: a randomized controlled study. J Cutan Aesthet Surg. 2020; 13:(3)197-203 https://doi.org/10.4103/JCAS.JCAS_12_20

Microneedling: monotherapy or adjuvant treatment?

02 January 2025
Volume 14 · Issue 1

Abstract

Microneedling, a minimally invasive procedure involving repeated puncturing of the skin with sterilized microneedles, has gained popularity for treating various dermatological concerns. Its ability to stimulate collagen production makes it effective for skin rejuvenation, scar reduction, and hair regrowth. Recent studies demonstrate its enhanced efficacy when combined with other treatments, such as minoxidil, platelet-rich plasma, and exosomes for hair regeneration. Additionally, microneedling shows promise in managing conditions like vitiligo and melasma when used alongside topical therapies. The expanding applications of microneedling highlight its versatility, with combination therapies proving more effective than monotherapies for optimal patient outcomes.

Skin care and skin health has risen to ever-increasing prominence in public opinion within recent years. A patient's satisfaction with the appearance of their skin should be even more pressing to the aesthetic practitioner when considering the fact that dermatological conditions, such as acne vulgaris, can significantly impair a person's psychosocial wellbeing, relationships and quality of life. Indeed, as an example, 25.7% of 723 cross-sectional survey participants with atrophic acne scars felt less attractive or were embarrassed or self-conscious because of their scars; furthermore, 8.3% reported being regularly verbally and/or physically abused because of their scars, and 43.2% felt that their scars had negatively impacted their relationships (Tan et al, 2021).

Microneedling, a process involving repetitive puncturing of the skin with sterilised microneedles, presents a minimally invasive modality that is fast gaining popularity, due to its ability to harness the potential of the body's own regenerative processes and its versatility for both at-home and professional use. It is most commonly used as a skin resurfacing and rejuvenation procedure, with the microwounds caused by the tiny needles of the microneedling device triggering collagen production through a downstream wound healing cascade. However, there is debate as to whether microneedling is more effective as either an adjuvant treatment or as a monotherapy for a growing number of applications. To prepare for an increasing variety of patient concerns, aesthetic professionals must be appraised of the benefits of microneedling as either a mono- or combination therapy for a range of different applications.

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