References

Lee HC, Thng TG, Goh CL. Oral tranexamic acid (TA) in the treatment of melasma: a retrospective analysis. J Am Acad Dermatol.. 2016; 75:(2)385-392 https://doi.org/1016/j.jaad.2016.03.001

Metz M. Treatments for chronic pruritus outside of the box. Exp Dermatol.. 2019; https://doi.org/1111/exd.14007

van Galen LS, Xu X, Koh MJA Eczema apps conformance with clinical guidelines: a systematic assessment of functions, tools and content. Br J Dermatol.. 2019; https://doi.org/10.1111/bjd.18152

Li CX, You ZX, Lin YX Skin microbiome differences relate to the grade of acne vulgaris. J Dermatol.. 2019; https://doi.org/1111/1346-8138.14952

Legat FJ. Is there still a role for UV therapy in itch treatment?. Exp Dermatol.. 2019; https://doi.org/10.1111/exd.14011

Research roundup

02 September 2019
Volume 8 · Issue 7

Abstract

In this regular feature, aesthetic nurse Claudia McGloin presents a brief synopsis of a range of recently published articles on medical aesthetics. Research roundup aims to provide an overview, rather than a detailed summary and critique, of the papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided at the end of each study summary

Melasma is a pigmentary disorder that is challenging to treat and especially common in people of Asian descent. Recently, oral tranexamic acid (TA) has shown potential for treating this condition.

This study evaluated treatment outcomes and adverse effects of oral TA treatment for melasma in an Asian population. The authors looked at data collected from January 2010 to June 2014 from patients who received oral TA for melasma in a tertiary dermatology centre.

The results of the study showed that a majority of the 561 patients who took part over a 4-month period saw an improvement in their melasma. The study also showed that 56 patients had no improvement, while two patients saw their skin condition worsen. Interestingly, patients in the study without a family history of melasma had better response rates than those with family history.

In conclusion to this study, the authors feel that oral TA may be an effective treatment for melasma.

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