References

Chernoff G. Combining topical dermal infused exosomes with injected calcium hydroxylapatite for enhanced tissue biostimulation. J Cosmet Dermatol. 2023; 22:15-27 https://doi.org/10.1111/jocd.15695

Jenssen M, Furberg AS, Jorde R, Wilsgaard T, Danielsen K. Effect of vitamin D supplementation on psoriasis severity in patients with lower-range serum 25-hydroxyvitamin D Levels: a randomized clinical trial. JAMA Dermatol. 2023; https://doi.org/10.1001/jamadermatol.2023.0357

Huang LH, Rau CS, Zeng WH, Lu TH, Wu YC, Chiu YH, Wu KM, Tsai CW, Lin CW, Wu CJ, Chung YC, Hsieh CH. A new technique for separating platelet-rich plasma by a copolymer device—without a centrifugation process. Biomed Pharmacother. 2022; 153 https://doi.org/10.1016/j.biopha.2022.113481

McCarty MF, Benzvi C, Vojdani A, Lerner A. Nutraceutical strategies for alleviation of UVB phototoxicity. Exp Dermatol. 2023; https://doi.org/10.1111/exd.14777

Research Roundup

02 May 2023
Volume 12 · Issue 4

Abstract

In this regular feature, aesthetic nurse Claudia McGloin presents a brief synopsis of a range of recently published articles on medical aesthetics. Research roundup aims to provide an overview, rather than a detailed summary and critique, of the papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided at the end of each study summary

Research into exosomes—tiny, sac-resembling structures formed inside cells—is growing rapidly. Exosomes transfer information between cells by delivering signalling molecules. With regard to its use, there are studies looking at combination treatments using exosomes for the purpose of biostimulation. It can also be used in treatments involving calcium hydroxylapatite (CaHA), platelet-rich plasma and platelet-rich fibrin matrix.

The aim of this study was to create safe protocols for improving the delivery of topical exosomes to enhance the quality of the skin, either by using them in a standalone treatment or in combination with injectable CaHA.

A total of 40 patients were involved. To test if the method alone would allow exosomes absorption, 20 of them had facial biostimulatory dermal infusion; five of them had facial bio stimulator infusion followed by CaHA injection to their faces; five others had exosome biostimulatory dermal infusion followed by hyperdiluted CaHA injection to their necks; five more had facial dilute CaHA injection without dermal infusion; the remaining five had their necks injected with hyperdiluted CaHA injection without dermal infusion.

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